Description
DESCRIPTION
Probiotic to support healthy weight management
- Assists in weight management when used with a program of reduced intake of dietary calories and increased physical activity
- Includes a combination of five proprietary human strains clinically studied in adults
- Supports gastrointestinal health and promotes a favourable gut flora
- Provides 50 billion CFU per capsule
HMF® Metabolic was specifically formulated with a combination of five proprietary probiotic strains, which were studied in a recent randomized, double-blind, placebo-controlled trial in adults.1 Results of the study demonstrated that HMF® Metabolic’s probiotic strains significantly increased quality of life scores, including general wellness and state of health.1 These strains have also been examined in various other preclinical and clinical studies for their beneficial health effects, including their ability to promote a healthy gut flora composition.2-6 Emerging research demonstrates that diet and weight play an important role in the composition of the intestinal microflora, with the typical Western diet and larger body composition being associated with a greater proportion of Firmicutes than Bacteroidetes.7 These alterations in the normal gut flora composition may impact intestinal function, including short-chain fatty acid production and energy metabolism.8 Available in a convenient, once-daily capsule format, HMF® Metabolic can be easily added to any lifestyle regimen to support an optimal gut flora composition and assist in weight management when used with a program of reduced intake of dietary calories and increased physical activity.
REFERENCES
1. Michael DR, Jack AA, Masetti G, Davies TS, Loxley KE, et al. Sci Rep. 2020 Mar; 10(1): 4183.
2. Michael DR, Moss JW, Calvente DL, Garaiova I, Plummer SF, et al. Benef Microbes. 2016 Jun; 7(3): 443-51.
3. Michael DR, Davies TS, Moss JWE, Calvente DL, Ramji DP, et al. Sci Rep. 2017 Jun; 7(1):2883.
4. Williams EA, Stimpson J, Wang D, Plummer S, Garaiova I, et al. Aliment Pharmacol Ther. 2009 Jan; 29(1): 97-103.
5. Madden JA, Plummer SF, Tang J, Garaiova I, Plummer NT, et al. Int Immunopharmacol. 2005 Jun; 5(6): 1091-7.
6. Plummer SF, Garaiova I, Sarvotham T, Cottrel, SL, Le Scouiller S, et al. Int J Antimicrob Agents. 2005 Jul; 26(1): 69-74.
7. Kobyliak N, Conte C, Cammarota G, Haley AP, Styriak I, et al. Nutr Metab (Lond). 2016 Feb; 13:14.
8. Cerdó T, García-Santos JA, G Bermúdez M, Campoy C. Nutrients. 2019 Mar; 11(3): 635.
INGREDIENTS
Medicinal Ingredients (per capsule):
Probiotic Consortium | 50 billion CFU
Lactobacillus acidophilus (CUL-60 & CUL-21) | 25.2 billion CFU
Lactiplantibacillus plantarum (CUL-66) | 16.5 billion CFU
Bifidobacterium animalis subsp. lactis (CUL-34) & Bifidobacterium bifidum (CUL-20) | 8.3 billion CFU
Non-Medicinal Ingredients: Hypromellose, cellulose, sunflower lecithin, silica. Ingredients used to maintain viability of probiotics (dipotassium phosphate, monopotassium phosphate, trehalose, sucrose, maltodextrin).
DOSING
Adults: Take 1 capsule daily, at least 2-3 hours before or after taking antibiotics, or as recommended by your healthcare practitioner. For weight management: Use for a minimum of 6 months to see beneficial effects.
CAUTIONS
Do not use this product if you are pregnant or have an immune-compromised condition. Consult your healthcare practitioner prior to use if you are breastfeeding, or have fever, vomiting, bloody diarrhoea or severe abdominal pain. Stop use and consult your healthcare practitioner if symptoms of digestive upset occur, worsen or persists beyond 3 days. Keep out of the reach of children.