Description
DESCRIPTION
Delayed-release pancreatic enzyme formulation
• Helps to decrease bloating after high-caloric, high-fat meals
• Aids digestion
• Provides a mixture of digestive enzymes, such as protease, amylase, lipase, chymotrypsin and trypsin
Improved formula
• Higher concentration of lipase, chymotrypsin and trypsin
• Formulated with delayed-release capsules for targeted release in the intestine
• New easier to swallow capsule format
Pancreatin is a digestive aid formula that helps to decrease bloating after high-caloric, high-fat meals. It provides a combination of pancreatic enzymes, including lipase, amylase and protease, which break down fats, carbohydrates and proteins, respectively.1 Chymotrypsin and trypsin are also present in pancreatic secretions and further contribute to protein digestion.1 Adequate activity of pancreatic enzymes is critical for proper nutrient digestion and absorption, including the absorption of fat-soluble vitamins.2,3 Pancreatin contains enzymes that act like those normally secreted by the pancreas, aiding digestion of nutrients. Supplementation with pancreatic enzymes has also been shown to significantly reduce the common postprandial complaints associated with caloric, high-fat meals, including bloating, gas and fullness.4 As pancreatic enzymes are sensitive to low pH, Pancreatin is specifically formulated with delayed-release capsules that resist stomach acid for targeted delivery to the duodenum and allowing optimal enzyme activity.
References
1. Whitcomb, DC, Lowe, ME. Dig Dis Sci. 2007; 52(1): 1-17.
2. Roxas, M. Altern Med Rev. 2008; 13(4): 307-14.
3. Hackert, T, Schütte, K, Malfertheiner, P. Viszeralmedizin. 2014; 30(3): 190-7.
4. Suarez, F, Levitt, MD, Adshead, J, Barkin, JS. Dig Dis Sci. 1999; 44(7): 1317-21.
INGREDIENTS
EACH CAPSULE CONTAINS: Pancreatic Enzymes (from porcine pancreas). . . . . . . . . . . . 370 mg Yielding/ Rendement Protease Activity. . . . . . . . . . . . . . . . . . . . . . . . 37000 USP Amylase Activity. . . . . . . . . . . . . . . . . . . . . . . . . . 37000 USP Lipase Activity . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8880 USP Trypsin (from porcine pancreas) . . . . . . . . . . . . . . .20 mg / 1500 USP Chymotrypsin (from bovine pancreas . . . . . . . . . .8 mg / 8000 USP Non-Medicinal Ingredients: Delayed-release capsule (hypromellose, gellan gum), cellulose, ascorbyl palmitate, silica, lactose Contains: Milk
DOSING
Recommended Adult Dose: Take one capsule three times daily, with each meal or immediately before a meal, or as recommended by your healthcare practitioner. Consult your healthcare practitioner for use beyond four weeks. Use the smallest effective dose which controls symptoms.
CAUTIONS
Risk Information: Do not use if you are sensitive to pancreatic enzymes or to pork proteins. Consult your healthcare practitioner prior to use if you are pregnant, breastfeeding, taking anticoagulant agents, anti-inflammatory agents or other enzyme products, have gastrointestinal lesions, diabetes, pancreatitis, pancreatic exocrine insufficiency or cystic fibrosis, or are having surgery. Consult your healthcare practitioner if symptoms persist or worsen. Hypersensitivity, nausea, vomiting, abdominal pain or heartburn have been known to occur; in which case discontinue use and consult your healthcare practitioner.